研究業績
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2015年
Feng, H., T. Miyakawa, N. Kitamura, M. Takeuchi, S.B. Park, S. Kishino, J. Ogawa, M. Tanokura. "Structure and reaction mechanism of a novel enone reductase." FEBS Journal, 282(8), 1526-1537 (2015).
Goto, T., Y.I. Kim, T. Furuzono, N. Takahashi, K. Yamakuni, H.E. Yang, Y. Li, R. Ohue, W. Nomura, T. Sugawara, R. Yu, N. Kitamura, S.B. Park, S. Kishino, J. Ogawa, T. Kawada. "10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARgamma and stimulates adipogenesis." Biochem. Biophys. Res. Commun., 459(4), 597-603 (2015).
Hibi, M., T. Kasahara, T. Kawashima, H. Yajima, S. Kozono, S.V. Smirnov, T. Kodera, M. Sugiyama, S. Shimizu, K. Yokozeki, J. Ogawa. "Multi-Enzymatic Synthesis of Optically Pure β-Hydroxy α-AminoAcids." Adv. Synth. Catal., 357(4), 767-774 (2015).
Hirata, A., S. Kishino, S.B. Park, M. Takeuchi, N. Kitamura, J. Ogawa. "A novel unsaturated fatty acid hydratase toward C16 to C22 fatty acids from Lactobacillus acidophilus." J. Lipid Res., 56, 1340-1350 (2015).
Horita, S., M. Kataoka, N. Kitamura, T. Nakagawa, T. Miyakawa, J. Ohtsuka, K. Nagata, S. Shimizu, M. Tanokura. "An Engineered Old Yellow Enzyme that Enables Efficient Synthesis of (4R,6R)-Actinol in a One-Pot Reduction System." ChemBioChem, 16(3), 440-445 (2015).
Kikukawa, H., E. Sakuradani, Y. Nishibaba, T. Okuda, A. Ando, J. Shima, S. Shimizu, J. Ogawa. "Production of cis-11-eicosenoic acid by Mortierella fungi." J. Appl. Microbiol., 118(3), 641-647 (2015).
Kikukawa, H., E. Sakuradani, A. Ando, T. Okuda, M. Ochiai, S. Shimizu, J. Ogawa. "Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4." J. Biotechnol., 208, 63-69 (2015).
Kikukawa, H., E. Sakuradani, M. Nakatani, A. Ando, T. Okuda, T. Sakamoto, M. Ochiai, S. Shimizu, J. Ogawa. "Gene targeting in the oil-producing fungus Mortierella alpina 1S-4 and construction of a strain producing a valuable polyunsaturated fatty acid by gene targeting." Curr. Genet., 61(4), 579-589 (2015).
Miyamoto, J., T. Mizukure, S.B. Park, S. Kishino, I. Kimura, K. Hirano, P. Bergamo, M. Rossi, T. Suzuki, M. Arita, J. Ogawa, S. Tanabe. "A gut microbial metabolite of linoleic acid, 10-hydrosxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40/MEK-ERK pathway." J. Biol. Chem., 290(5), 2902-2918 (2015).
Nakato, M., M. Matsuo, N. Kono, M. Arita, H. Arai, J. Ogawa, N. Kioka, K. Ueda. "Neurite outgrowth stimulation by n-3 and n-6 PUFAs of phospholipids in apoE-containing lipoproteins secreted from glial cells." J. Lipid Res., 56, 1880-1890 (2015).
Nanthirudjanar, T., H. Furumoto, J. Zheng, Y.L. Kim, T. Goto, N. Takahashi, T. Kawada, S.B. Park, A. Hirata, N. Kitamura, S. Kishino, J. Ogawa, T. Hirata, T. Sugawara. "Gut microbial fatty acid metabolites reduce triacylglycerol levels in hepatocytes." Lipids, 50(11), 1093-1102 (2015).
Nojiri, M., M. Hibi, H. Shizawa, N. Horinouchi, Y. Yasohara, S. Takahashi, J. Ogawa. "Imidase catalyzing desymmetric imide hydrolysis forming optically active 3-substituted glutaric acid monoamides for the synthesis of gamma-aminobutyric acid (GABA) analogs." Appl. Microbiol. Biotechnol., 99(23), 9961-9969 (2015).
Ogawa, J.. "New lipid science in our inner ecosystem." Eur. J. Lipid Sci. Technol., 117(5), 577-578 (2015).
小川 順. "脂質バランス栄養食品を創出する新規オメガ3脂肪酸素材の開発." シーズ創出ステージ・食品-機能性分野 農林水産業・食品産業科学技術研究推進事業 研究紹介 2015, 41-42, 農林水産省 農林水産技術会議事務局 研究推進課・公益社団法人 農林水産・食品産業技術振興会 (2015).
小川 順, 岸野重信. "食事脂質の腸内細菌代謝と代謝産物の生理機能." 消化と吸収, 37(2), 80-82 (2015).
小川 順, 岸野重信. "第30章 乳酸菌代謝の機能性食品素材開発への応用." 発酵・醸造食品の最前線 第U編 醸造微生物の最新技術, 250-256, 北本勝ひこ監修 株式会社シーエムシー出版 (2015).
小川 順. "JBAニュース 「3研究会 合同シンポジウム 藻類に託されるグリーンビジネス成長戦略のゆくえ」." バイオサイエンスとインダストリー, 73(2), 178-179 (2015).
小川 順. 第4章 グリーンバイオ俯瞰ワークショップ 4-5.セッション3 微生物機能 4-5-3 生物間インターフェースにおける機能的微生物コミュニティの解析と応用 〜複合微生物系の解析による新たな微生物機能制御技術の開発〜 俯瞰ワークショップ報告書 ライフサイエンス・臨床医学分野 〜主にグリーンバイオ分野を中心に〜. 独立行政法人科学技術振興機構 研究開発戦略センター ライフサイエンス・臨床医学ユニット, 45-47 (2015) .
Okuda, T., A. Ando, H. Negoro, H. Kikukawa, T. Sakamoto, E. Sakuradani, S. Shimizu, J. Ogawa. "Omega-3 eicosatetraenoic acid production by molecular breeding of the mutant strain S14 derived from Mortierella alpina 1S-4." J. Biosci. Bioeng., 120(3), 299-304 (2015).
Okuda, T., A. Ando, H. Negoro, T. Muratsubaki, H. Kikukawa, T. Sakamoto, E. Sakuradani, S. Shimizu, J. Ogawa. "Eicosapentaenoic acid (EPA) producing by an oleginous fungus Mortierella alpina expressing heterologous Δ17-desaturase gene under ordinary temperature." Eur. J. Lipid Sci. Technol., 117(12), 1919-1927 (2015).
Takeuchi, M., S. Kishino, S.B. Park, N. Kitamura, J. Ogawa. "Characterization of hydroxy fatty acid dehydrogenase involved in polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a." J. Mol. Catal., B Enzym. 117, 7-12 (2015).
Takeuchi, M., S. Kishino, A. Hirata, S.B. Park, N. Kitamura, J. Ogawa. "Characterization of the linoleic acid Δ9 hydratase catalyzing the first step of polyunsaturated fatty acid saturation metabolism in Lactobacillus plantarum AKU 1009a." J. Biosci. Bioeng., 119(6), 636-641 (2015).
谷村あゆみ, 小川 順, 島 純. "酵母を用いた一貫バイオプロセス -デンプン系非可食原料からのバイオ燃料生産に向けて-." BIOINDUSTRY, 32(10), 60-65 (2015).
Tanimura, A., M. Kikukawa, S. Yamaguchi, S. Kishino, J. Ogawa, J. Shima. "Direct ethanol production from starch using a natural isolate, Scheffersomyces shehatae : Toward consolidated bioprocessing." Sci. Rep., 5;9593 (2015).
Tsuda, K., H. Nagano, A. Ando, J. Shima, J. Ogawa. "Isolation and characterization of psychrotolerant endospore-forming Sporosarcina species associated with minced fish meat (surimi)." Int. J. Food Microbiol., 199(16), 15-22 (2015).
Yamada, M., K. Adachi, N. Ogawa, S. Kishino, J. Ogawa, M. Kataoka, S. Shimizu, K. Isobe. "A new aldehyde oxidase catalyzing conversion of glycolaldehyde to glycolate from Burkholderia sp. AIU 129." J. Biosci. Bioeng., 119(4), 410-415 (2015).
Yonejima, Y., K. Hisa, M. Kawaguchi, H. Ashitani, T. Koyama, Y. Usamikrank, N. Kishida, S. Kishino, J. Ogawa. "Lactic acid bacteria-containing chocolate as a practical probiotic Product with increased acid tolerance." Biocatal Agric Biotechnol, 4(4), 773-777 (2015).
Yoshiyama, Y., K. Tanaka, K. Yoshiyama, M. Hibi, J. Ogawa, J. Shima. "Trehalose accumulation enhances tolerance of Saccharomyces cerevisiae to acetic acid." J. Biosci. Bioeng., 119(2), 172-175 (2015).
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