研究業績
1992 / 1993 / 1994 / 1995 / 1996 / 1997 / 1998 / 1999 / 2000 / 2001 / 2002 / 2003 / 2004 / 2005
2006 / 2007 / 2008 / 2009 / 2010 / 2011 / 2012 / 2013 / 2014 / 2015 / 2016 / 2017 / 2018 / 2019
2020 / 2021 / 2022 / 2023 / 2024
2001年
Baba, N., M. K. Alam, Y. Mori, S. S. Haider, M. Tanaka, S. Nakajima, S. Shimizu. "A first synthesis of a phosphatidylcholine bearing docosahexaenoic and tetracosahexaenoic acids." J. Chem. Soc., Perkin Trans., 1, 221-223 (2001).
Goda, M., Y. Hashimoto, S. Shimizu, M. Kobayashi. "Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage." J. Biol. Chem., 276, 23480-23485 (2001).
Hidalgo, A.-R. G. D., M. A. Akond, K. Kita, M. Kataoka, S. Shimizu. "Isolation and primary structural analysis of two conjugated polyketone reductases from Candida parapsilosis." Biosci. Biotechnol. Biochem., 65(12), 2785-2788 (2001).
Kataoka, M., M. Sasaki, A.-R. G. D. Hidalgo, M. Nakano, S. Shimizu. "Glycolic acid production using ethylene glycol-oxidizing microorganisms." Biosci. Biotechnol. Biochem., 65(10), 2265-2270 (2001).
Kizaki, N., Y. Yasohara, J. Hasegawa, M. Wada, M. Kataoka, S. Shimizu. "Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes." Appl. Microbiol. Biotechnol., 55, 590-595 (2001).
Li, Q. S., J. Ogawa, S. Shimizu. "Critical role of the residue size at position 87 in H2O2-dependent substrate hydroxylation activity and H2O2 inactivation of cytchrome P450BM-3." Biochem. Biophys. Res. Commun., 280, 1258-1261 (2001).
Li, Q. S., J. Ogawa, R. D. Schmid, S. Shimizu. "Residue size at position 87 of cytchrome P450 BM-3 determines its stereoselectivity in propylbenzene and 3-chlorostyrene oxidation." FEBS Lett., 508, 249-252 (2001).
Li, Q. S., J. Ogawa, R. D. Schmid, S. Shimizu. "Engineering cytchrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons." Appl. Environ. Microbiol., 67, 5735-5739 (2001).
Nakano, N., N. Shirasaka, K. Masuoka, T. Murakami, T. Watanabe, K. Kobata, S. Shimizu, H. Yoshizumi. "Inhibitory effects of capsaicinoids on fatty acid desaturation in a rat liver cell line." Biosci. Biotechnol. Biochem., 65(8), 1859-1863 (2001) .
Ogawa, J., K. Matsumura, S. Kishino, Y. Omura, S. Shimizu. "Conjugated linoleic acid (CLA) accumulation via 10-hydroxy-12-octadecaenoic acid during microaerobic transformation of linoleic acid by Lactobacillus acidophilus." Appl. Environ. Microbiol., 67, 1246-1252 (2001).
Ogawa, J., A. Ryono, S-X. Xie, R.M. Vohra, R. Indrati, M. Akamatsu, H. Miyagawa, T. Ueno, S. Shimizu. "Separative preparation of the four stereoisomers of β-methylphenylalanine with N-carbamoyl amino acid amidohydrolases." J. Molec. Catal. B: Enzymatic, 12, 71-75 (2001).
Ogawa, J., C-L. Soong, M. Ito, S. Shimizu. "Enzymatic production of pyruvate from fumarate: an application of microbial cyclic-imide-transforming pathway." J. Molec. Catal. B: Enzymatic, 11, 355-359 (2001).
小川 順, 宋 子良, 清水 昌. 微生物における環状アミド代謝の多様性とその応用 -多様性解明に端を発するバイオプロセスの開発の流れ- . 化学と生物, 39(5), 333-339 (2001).
Ogawa, J., S. Takeda, S-X. Xie, H. Hatanaka, T. Ashikari, T. Amachi, S. Shimizu. "Purification, characterization and gene cloning of purine nucleosidase from Ochrobactrum anthropi." Appl. Environ. Microbiol., 67, 1783-1787 (2001).
Oiyango, A. N., T. Inoue, S. Nakajima, N. Baba, T. Kaneko, M. Matsuno, S. Shimizu. "Synthesis and stability of phosphatidylcholines bearing polyenopic acid hydroperoxides at the sn-2 position." Angew. Chem. Int. Ed., 40, 1755-17757 (2001).
ヘルマン・サーム, 清水 昌. Corynebacterium glutamicumにおける経路設計と代謝工学. バイオサイエンスとインダストリー, 59, 17-21 (2001).
清水 昌. 微生物生産の将来を嘱望する、「高分子科学とバイオテクノロジーとのキャッチボール -21世紀における高分子とバイオテクノロジーの融合とその将来-」社団法人高分子学会編, エヌ・ティー・エス, 東京, pp. 47-64 (2001).
清水 昌. 生体触媒とバイオプロセス・スーパー生体触媒の探索と開発. 触媒. 43, 190-195 (2001).
Shimizu, S. Vitamins and related compounds: microbial production. Biotechnology, vol. 10, Reed, G., Rehm, H-J., eds., VCH, Weinheim, 320-340 (2001).
Shimizu, S., M. Kataoka, K. Honda, K. Sakamoto. "Lactone-ring-cleaving enzymes of microorganisms: their diversity and applications." J. Biotechnol., 92, 187-194 (2001).
清水 昌, 小川 順, 櫻谷英治. 有用油脂生産微生物の代謝工学. バイオサイエンスとインダストリー, 59, 451-454 (2001).
清水 昌, 小林達彦, 片岡道彦, 小川 順. アクリルアミド発酵、アデノシルホモシステイン発酵、アデノシルメチオニン発酵、カプロン酸発酵、グリセロール発酵、CoA発酵、多価不飽和脂肪酸発酵、ニコチンアミド発酵、D-パントラクトン発酵、「発酵ハンドブック」栃倉辰六郎、山田秀明、別府輝彦、左右田健次監修, 共立出版, 東京、pp. 7-9, 26, 27, 112, 127-128, 161-162, 267-271, 313, 325-326, 660-661 (2001).
Soong, C-L., J. Ogawa, S. Shimizu. "Cyclic ureide and imide metabolism in microorganisms producing a d-hydantoinase useful for d-amino acid production." J. Molec. Catal. B: Enzymatic, 12, 61-70 (2001).
Soong, C-L., J. Ogawa, S. Shimizu. "Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: Analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase." Biochem. Biophys. Res. Commun., 286, 222-226 (2001)
Tsujimura, S., H. Tatsumi, J. Ogawa, S. Shimizu, K. Kano, T. Ikeda. "Bioelectrocatalytic reduction of dioxygen to water at at neutral pH using bilirubin oxidase as an enzyme and 2,2'-azinobis (3-ethylbenzothiazolin-6-sulfonate) as an electron transfer mediator." J. Electroanalytical Chemistry, 496, 69-75 (2001).
Yamada, H., S. Shimizu, M. Kobayashi. "Hydratases involved in nitrile conversion: screening, characterization and application." Chemical Records, 1, 152-161 (2001).
Yasohara, Y., N. Kizaki, J. Hasegawa, M. Wada, M. Kataoka, S. Shimizu. "Stereoselective reduction of alkyl 3-oxobutanoate by carbonyl reductase from Candida magnoliae." Tetrahedron: Asymmetry., 12, 1713-1718 (2001).
Yoshizumi, A., M. Wada, H. Takagi, S. Shimizu, S. Nakamori. "Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding monovalent cation-activated Levodione reductase from Corynebacterium aquaticum M-13." Biosci. Biotechnol. Biochem., 65(4), 830-836 (2001).
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