発表論文
2001-2002
A.-R. G. D. Hidalgo, M. A. Akond, K. Kita, M. Kataoka, S. Shimizu: Isolation and primary structure analysis of two conjugated polyketone reductases from Candida parapsilosis. Biosci. Biotechnol. Biochem., 65, 2785-2788 (2001)
N. Kizaki, Y. Yasohara, J. Hasegawa, M. Wada, M. Kataoka, S. Shimizu: Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes. Appl. Microbiol. Biotechnol., 55, 590-595 (2001)
J. Ogawa, A. Ryono, S-X. Xie, R.M. Vohra, R. Indrati, M. Akamatsu, H. Miyagawa, T. Ueno, S. Shimizu: Separative preparation of the four stereoisomers of b-methylphenylalanine with N-carbamoyl amino acid amidohydrolases. J. Molec. Catal. B: Enzymatic, 12, 71-75 (2001)
清水 昌: 生体触媒とバイオプロセス・スーパー生体触媒の探索と開発. 触媒. 43, 190-195 (2001)
A. Yoshizumi, M. Wada, H. Takagi, S. Shimizu, S. Nakamori: Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding monovalent cation-activated Levodione reductase from Corynebacterium aquaticum M-13. Biosci. Biotechnol. Biochem., 65, 830-836 (2001)
Y. Yasohara, N. Kizaki, J. Hasegawa, M. Wada, M. Kataoka, S. Shimizu: Stereoselective reduction of alkyl 3-oxobutanoate by carbonyl reductase from Candida magnoliae. Tetrahedron: Asymmetry, 12, 1713-1718 (2001)
T. Tsujigami, T. Sugai, H. Ohta: Microbial asymmetric reduction of _-hydroxyketones in the anti-Prelog selectivity. Tetrahedron Asymmetry, 12, 2543-2549 (2001)
太田博道: 生体触媒の特徴を生かした有機化学. 触媒学会, 43, 196-201 (2001)
D. Kato, S. Mitsuda, H. Ohta: Microbial deracemization of α-substituted carboxylic acids. Org. Lett., 4, 371-373 (2002)
H. Ashida, K. Yamamoto, H. Kumagai: Enzymatic syntheses of T antigen-containing glycolipid mimicry using the transglycosylation activity of endo-α-N-acetylgalactosaminidase. Carbohyd. Res. , 330, 487-493 (2001)
K. Haneda, T. Inazu, M. Mizuno, R. Iguchi, H. Tanabe, K. Fujimori, K. Yamamoto, H. Kumagai, K. Tsumori, E. Munekata: Chemo-enzymatic synthesis of a bioactive peptide containing a glutamine-linked oligosaccharide and its characterization. Biochim. Biophys. Acta, 1526, 242-248 (2001)
山本憲二、藤森賢也、島田義啓、熊谷英彦、羽田勝二、稲津敏行、伊藤和央、南浦能至: 微生物のエンドグリコシダーゼを用いた生理活性複合糖質の化学-酵素合成. 応用糖質科学, 48, 2, 195-203 (2001)
T. Kato, K. Fujita, M. Takeuchi, K. Kobayashi, S. Natsuka, K. Ikura, H. Kumagai, K. Yamamoto: Identification of an endo-β-N-acetylglucosaminidase gene in Caenorhabditis elegans and its expression in Escherichia coli. Glycobiology, in press (2002)
M. Fujihashi, Y.-W. Zhang, Y. Higuchi, X.-Y. Li, T. Koyama, K. Miki: Crystal structure of cis-prenyl chain elongating enzyme, undecaprenyl diphosphate synthase. Proc. Natl. Acad. Sci.,U. S. A., 98, 4337-4342 (2001)
Y. Kharel, Y.-W. Zhang, M. Fujihashi, K. Miki, T. Koyama: Identification of Significant Residues for Homoallylic Substrate Binding of Micrococcus luteus B-P 26 Undecaprenyl Diphosphate Synthase. J. Biol. Chem., 276, 28459-28464 (2001)
M. Nagaki, K. Kimura, H. Kimura, Y. Maki, E. Goto, T. Nishino, T. Koyama: Artificial substrates of medium-chain elongation enzymes, hexaprenyl- and heptaprenyl diphosphate synthases. Bioorg. Med. Chem. Lett., 11, 2157-2159 (2001)
M. Nagaki, H. Yamamoto, A. Takahashi, Y.
Maki, J. Ishibashi, T. Nishino, T. Koyama: Substrate specificity
of thermostable farnesyl diphosphate synthase with respect to
4-alkyl group homologs of isopentenyl diphosphate. J. Mol. Catal.
B: Enzymatic, in press (2002)
2000
片岡道彦、喜多恵子、清水 昌: 組換え大腸菌を利用した光学活性化合物の生産プロセス. 化学と生物, 38, 313-318 (2000)
J.-Q. Liu, T. Dairi, N. Itoh, M. Kataoka, S. Shimizu, H: Yamada: Diversity of microbial threonine aldolases and their application. J. Molec. Catal. B: Enzymatic, 10, 107-115 (2000)
J-Q. Liu, M. Odani, T. Yasuoka, T. Dairi, N. Itoh, M. Kataoka, S. Shimizu, H. Yamada: Gene cloning and overproduction of low-specificity D-threonine aldolase from Alcaligenes xylosoxidans and its application for production of a key intermediate for Parkinsonism drug. Appl. Microbiol. Biotechnol., 54, 44-51 (2000)
Y. Yasohara, N. Kizaki, J. Hasegawa, M. Wada, M. Kataoka, S. Shimizu: Molecular cloning and overexpression of the gene encoding an NADPH-dependent carbonyl reductase from Candida magnoliae, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate. Biosci. Biotechnol. Biochem., 64, 1430-1436 (2000)
M. Suzuki, T. yamazaki, H. Ohta, K. Shima, K. Ohi, S. Nishiyama, N-Carbamylamino alcohols as the pricursors of oxazolidinones via nitrosation-deamination reaction. Synlett., 189-192 (2000)
A. Kuboki, T. Ishihara, E. Kobayashi, H. Ohta, T. Ishii, A. Inoue, S, Mitsuda, T. Miyazaki, Y. Kajihara, T. Sugai: Synthesis of regioselectively protected forms of cytidine based on the enzyme-catalyzed deacetylation as the key step. Biosci. Biotechnol. Biochem., 64, 363-368 (2000)
K. Matoishi, S. Hanzawa, H. Kakidani, M. Suzuki, T. Sugai, H. Ohta: The first synthesis of both enantiomers of [a-2H]phenylacetic acid in high enantiomeric excess. J. C. S. Chem. Commun., 1519-1520 (2000)
T. Yamazaki, A. Kuboki, H. Ohta, T. Mitzel, L. A. Paquette, T. Sugai: Yamadazyma farinosa IFO 10896-mediated reduction of 4,4-dimethoxy-2-butanone as the key-step for the preparatation of 1,3-diols with unsymmetrical substituents. Synth. Commun., 30, 3061-3072 (2000)
H. Ashida, H. Tamaki, T. Fujimoto, K. Yamamoto, H. Kumagai: Molecular cloning of cDNA encoding α-N-acetylgalactosaminidase from Acremonium sp.and its expression in yeast. Arch. Biochem. Biophys., 384, 2, 305-310 (2000)
H. Ashida, K. Yamamoto, H. Kumagai: Trypsin inhibitory activity of bovine fetuin de-O-glycosylated by endo-α-N-acetylgalactosaminidase. Biosci. Biotech. Biochem., 64, 10, 2266-2268 (2000)
H. Ashida, K. Yamamoto, T. Murata, T. Usui, H. Kumagai: Characterization of endo-α-N-acetylgalactosaminidase from Bacillus sp.and syntheses of neo-oligosaccharides using its transglycosylation activity. Arch. Biochem. Biophys., 373, 2, 394-400 (2000)
M. Xiao, K. Tanaka, X. Qian, K. Yamamoto, H. Kumagai: High-yield production and characterization of α-galactosidase from Bifidobacterium breve grown on raffinose. Biotechnol. Lett., 22, 747-751 (2000)
M. Nagaki, S. Sato, Y. Maki, T. Nishino, T. Koyama: Artificial substrates for undecaprenyl diphosphate synthase from Micrococcus luteus B-P 26. J. Mol. Catal. B: Enzymatic, 9, 33-38 (2000)
T. Koyama, Y. Gotoh, T. Nishino: Intersubunit location of the active site of farnesyl diphosphate synthase -Reconstitution of active enzymes by hybrid-type heteromeric dimers of site-directed mutants. Biochemistry, 39, 463-469 (2000)
M. Nagaki, A. Takaya, Y. Maki, J. Ishibashi, T. Nishino, T. Koyama: One-pot syntheses of the sex pheromone homologs of a codling moth, Laspeyresia promonella L. J. Mol. Catal. B: Enzymatic, 10, 517-522 (2000)
Y.-W. Zhang, Y. Kharel, T. Koyama: Overexpression, purification, and characterization of selenomethionyl farnesyl diphosphate synthase of Bacillus stearothermophilus. J. Mol. Catal. B: Enzymatic., 10, 623-630 (2000)
K. Hirooka, S. Ohnuma, A. Koike-Takeshita, T. Koyama, T. Nishino: Mechanism of product chain length determination for heptaprenyl diphosphate synthase from Bacillus stearothermophilus. Eur. J. Biochem., 267, 4520-4528 (2000)
Y.-W. Zhang, X.-Y. Li, T. Koyama: Chain length determination of prenyltransferases: Both heteromeric subunits of medium-chain (E)-prenyl diphosphate synthase are involved in the product chain length determination. Biochemistry, 39, 12717-12722 (2000)
K. Fujikura, Y.-W. Zhang, H. Yoshizaki, T. Nishino, T. Koyama: Significance of Asn-77 and Trp-78 in the catalytic function of undecaprenyl diphosphate synthase of Micrococcus luteus B-P 26, J. Biochem. 128, 917-922 (2000)
M. Nagaki, S., Sato, Y. Maki, T. Nishino, T. Koyama: An artificial substrate for undecaprenyl diphosphate synthase from Micrococcus luteus B-P 26. Catal. Commun., 1 , 33-35 (2000)
N. Ohya, Y. Tanaka, R. Wititsuwannakul, T. Koyama: Activity of rubber transferase and rubber particle size in Hevea Latex. J. Rub. Res., 3, 214-221 (2000)
1999
M. Kataoka, K. Yamamoto, H. Kawabata, M. Wada, K. Kita, H. Yanase, S. Shimizu: Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes. Appl. Microbiol. Biotechnol., 51, 486-490 (1999)
K. Kita, T. Fukura, K. Nakase, K. Okamoto, H. Yanase, M. Kataoka, S. Shimizu: Cloning, overexpression, and mutagenesis of the Sporobolomyces salmonicolor AKU4429 gene encoding a new aldehyde reductase, which catalyzes the stereoselective reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate. Appl. Environ. Microbiol., 65, 5207-5211 (1999)
K. Kita, M. Kataoka, S. Shimizu: Diversity of 4-chloroacetoacetate ethyl ester-reducing enzymes in yeasts and their application to chiral alcohol synthesis. J. Biosci. Bioeng., 88, 591-598 (1999)
K. Kita, K. Nakase, H. Yanase, M. Kataoka, S. Shimizu: Purification and characterization of new aldehyde reductases from Sporobolomyces salmonicolor AKU4429. J. Mol. Catalysis: B Enzymatic., 6, 305-313 (1999)
J-Q. Liu, M. Odani, T. Dairi, N. Itoh, S. Shimizu, H. Yamada: A new route to L-threo-3-[4-(methylthio)phenylserine], a key intermediate for the synthesis of antibiotics: Recombinat low-specificity D-threonine aldolase-catalyzed stereospecific resolution. Appl. Microbiol. Biotechnol., 51, 586-591 (1999)
J. Ogawa, A. Ryono, S-X. Xie, R.M. Vohra, R. Indrati, H. Miyakawa, T. Ueno, Y. Ikenaka, H. Nanba, S. Takahashi, S. Shimizu: b-Carbon stereoselectivity of N-carbamoyl-D-a-amino acid amidohydrolase for a,b-diastereomeric amino acids. Appl. Microbiol. Biotechnol., 52, 797-801 (1999)
J. Ogawa, A. Ryono, S-X. Xie, R.M. Vohra, R. Indrati, H Miyakawa, T Ueno, S. Shimizu: Simultaneous recognition of two chiral centers in a,b-diastereomeric amino acids by N-carbamoyl-L-a-amino acid amidohydrolase from Alcaligenes xylosoxidans. Biotechnol Lett., 21, 711-713 (1999)
J. Ogawa, S. Shimizu: Novel microbial enzymes for the industrial production of useful compounds: new applications derived from traditional screening. Trends Biotechnol., 17, 13-21 (1999)
J. Ogawa, S-X. Xie, S. Shimizu: Production of (R)-3-pentyn-2-ol through stereospecific hydrolysis of racemic 3-pentyn-2-ol esters with microbial enzymes. Appl. Microbiol. Biotechnol., 51, 53-57 (1999)
J. Ogawa, S-X. Xie, S. Shimizu: Stereoinversion of optically active 3-pentyn-2-ol by Nocardia species. Biotechnol. Lett., 21, 331-335 (1999)
清水 昌：微生物によるビタミン類の製造研究. ビタミン, 73, 713-720 (1999)
M. Wada, H. Kawabata, M. Kataoka, Y. Yasohara, N. Kizaki, J. Hasegawa, S. Shimizu: Purification and characterization of an aldehyde reductase from Candida magnoliae. J. Mol. Catalysis: B Enzymatic., 6, 333-339 (1999)
M. Wada, H. Kawabata, A. Yoshizumi, M. Kataoka, S. Nakamori, Y. Yasohara, N. Kizaki, J. Hasegawa, S. Shimizu: Occurrence of multiple ehtyl 4-chloro-3-oxobutanoate-reducing enzymes in Canadida magnoliae. J. Biosci. Bioeng., 87, 144-148 (1999)
M. Wada, T. Matsumoto, S. Nakamori, M. Sakamoto, M. Kataoka, J.-Q. Liu, N. Itoh, H. Yamada, S. Shimizu: Purification and characterization of a novel enzyme, L-threo-3-hydroxyaspartate dehydratase, from Pseudomonas sp. T62. FEMS Microbiol. Lett., 179, 147-151 (1999)
M. Wada, A. Yoshizumi, S. Nakamori, S. Shimizu. Purification and characterization of monovalent cation-activated Levodione reductase from Corynebacterium aquaticum M-13. Appl. Environ. Microbiol., 65, 4399-4403 (1999)
Y. Yasohara, N. Kizaki, J. Hasegawa, S. Takahashi, M. Wada, M. Kataoka, S. Shimizu: Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction. Appl. Microbiol. Biotechnol., 51, 847-851 (1999)
S-X., Xie, J. Ogawa, S. Shimizu: NAD+-dependent (S)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by Nocardia fusca AKU 2123. Biosci. Biotechnol. Biochem., 63, 1721-1729 (1999)
S-X. Xie, J. Ogawa, S. Shimizu: Production of (R)-3-pentyn-2-ol through stereoinversion of racemic 3-pentyn-2-ol by Nocardia fusca AKU 2123. Appl. Microbiol. Biotechnol., 52, 327-331 (1999)
M. Bakke, H. Ohta, U. Kazmaier, T. Sugai: Action of L-aminoacylase and L-amino acid oxidase on 2-amino-3-methyl-4-pentenoic acid [Δ(4)-dehydroisoleucine and alloisoleucine] stereoisomers: An alternative route to stereochemically pure compound and the application to the synthesis of (R)-2-methyl-1-butanol. Synthesis, 1671-1677 (1999)
Y. Fukuyama, K. Matoishi, M. Iwasaki, E. Takizawa, M. Miyazaki, H. Ohta, S. Hanzawa, H. Kakidani, T. Sugai: Preparative-scale enzyme-catalyzed synthesis of (R)-α-fluorophenylacetatic acid. Biosci. Biotechnol. Biochem., 63, 1164-1166 (1999)
A. Sakai, M. Bakke, H. Ohta, H. Kosugi, T. Sugai, Synthesis of (Rc, Ss)-1,1,1-trifluoro-3-(p-tolylsulfinyl)-2-propanol by an asymmetric reduction with a yeast, Yamadazyma farinose, as a key-step. Chem. Lett., 1255-1256 (1999)
S. Akiba, K. Yamamoto, H. Kumagai: Transglycosylation activity of the endo-β-1,4-glucanase from Aspergillus niger IFO31125 and its application. J. Biosci. Bioeng., 87 (5), 576-580 (1999)
M. Fujihashi, N. Shimizu, Y.-W. Zhang, T. Koyama, K. Miki: Crystallization and preliminary X-ray diffraction studies of undecaprenyl diphosphate synthase from Micrococcus luteus B-P 26. Acta Crystallographica Section D, 55, 1606-1607 (1999)
Y. -W. Zhang, X. -Y. Li, H. Sugawara, T. Koyama: Site-directed mutagenesis of the conserved residues in the component I of Bacillus subtilis heptaprenyl diphosphate synthase. Biochemistry, 38 (44), 14638-14643 (1999)
Y.-W. Zhang, T. Koyama: Bacillus subtilis heptaprenyl diphosphate synthase: A unique enzyme composed of two dissociable heterosubunits. Recent Res. Develpure & Applied Chem., 3, 209-223 (1999)
T. Koyama: Molecular Analysis of Prenyl Chain Elongating Enzymes. Biosci. Biotechnol. Biochem., 63, 1671-1676 (1999)
1998
M. Kataoka, L.P.S. Rohani, M. Wada, K. Kita, H. Yanase, I. Urabe, S. Shimizu: Escherichia coli tansformant expressing the glucose dehydrogenase gene from Bacillus megaterium as a cofactor regenerator in a chiral alcohol production system. Biosci. Biotech. Biochem., 62, 167-169 (1998)
J-Q. Liu, T. Dairi, N. Itoh, M. Kataoka, S. Shimizu, H. Yamada: Gene cloning, biochemical characterization and physiological role o a thermostable low-specificity L-threonine aldolase from Escherichia coli. Eur. J. Biochem., 255, 220-226 (1998)
J-Q. Liu, T. Dairi, N. Itoh, M. Kataoka, S. Shimizu, H. Yamada: A novel metal-activated pyridoxl enzyme with a unique primary structure, low specificity D-threonine aldolase from Arthrobacter sp. strain DK-38. J. Biol. Chem., 27, 16678-16685 (1998)
J-Q. Liu, S. Itoh, T. Dairi, N. Itoh, M. Kataoka, S. Shimizu, H. Yamada: Gene cloning, nucleotide sequencing, purification, and characterization of low-specific L-threonine aldolase from Pseudomonas sp. NCIMB 10558. Appl. Environ. Microbiol., 64, 549-554 (1998)
J-Q. Liu, S. Ito, T. Dairi, N. Itoh, S. Shimizu, H. Yamada: Low-specificity L-threonine aldolase of Pseudomonas sp. NCIMB 10558: purification, characterization and its application to b-hydroxy-a-amino acid synthesis. Appl. Microbiol. Biotechnol., 49, 702-708 (1998)
S. Shimizu, M. Kataoka, K. Kita: Chiral alcohol synthesis with yeast carbonyl reductases. J. Mol. Catalysis B: Enzymatic, 5, 321-325 (1998)
M. Wada, M. Kataoka, H. Kawabata, Y. Yasohara, N. Kizaki, J. Hasegawa, S. Shimizu: Purification and characterization of NADPH-dependent carbonyl reductase, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate, from Candida magnoliae. Biosci. Biotechnol. Biochem., 62, 280-285 (1998)
M. Wada, M. Sakamoto, M. Kataoka, J-Q. Liu, H. Yamada, S. Shimizu: Distribution of threonine aldolase activity with different stereospecificities in aerobic bacteria. Biosci. Biotechnol. Biochem., 62, 1586-1588 (1998)
S-X. Xie, J. Ogawa, S. Shimizu: (S)-3-Pentyn-2-ol production through microbial enzyme-catalyzed, highly enantioselective hydrolysis of racemic 3-pentyn-2-ol esters. Biotechnol. Lett., 20, 935-938 (1998)
K. Matoishi, A. Sano, N. Imai, T. Yamazaki, M. Yokoyama, T. Sugai, H. Ohta: Rhodococcus rhodochrous IFO 15564-mediated hydrolysis of alicyclic nitriles and amides: Stereoselectivity and use for kinetic resolution and asymmetrization. Tetrahedron: Asymmetry, 9, 1097-1102 (1998).
S. Akiba, K. Yamamoto, H. Kumagai: Effect of carbohydrate chain on surface net charge and hydrophobicity of glycoproteins. Biosci. Biotech. Biochem., 62 (11), 2171-2176 (1998)
K. Haneda, T. Inazu, M. Mizuno, R. Iguchi, K. Yamamoto, H. Kumagai, S. Aimoto, H. Suzuki, T. Noda: Chemo-enzymatic synthesis of calcitonin derivatives containing N-Linked oligosaccharides. Bioorg. Med. Chem. Lett., 8, 1303-1306 (1998)
K. Yamamoto, K. Fujimori, K. Haneda, M. Mizuno, T. Inazu, H. Kumagai: Chemo-enzymatic synthesis of a novel glycopeptide using a microbial endoglycosidase. Carbohyd. Res., 305, 415-422 (1998)
K. Yamamoto, T. Tanaka, K. Fujimori, C.-S. Kang, H. Ebihara, J. Kanamori, S. Kadowaki, T. Tochikura, H. Kumagai: Characterization of Bacillus sp. endo-β-N-acetylglucosaminidase and its application to deglycosylation of hen ovomucoid. Biotechnol. Appl. Biochem., 28 (3), 235-242 (1998)
N. Shimizu, T. Koyama and K. Ogura: Molecular cloning, expression, and characterization of the genes encoding the two essential protein components of Micrococcus luteus B-P 26 hexaprenyl diphosphate synthase. J. Bacteriol., 180 (6), 1578-1581 (1998)
S. Ohnuma, H. Hemmi, T. Koyama, K. Ogura, T. Nishino: Recognition of allylic substrates in Sulfolobus acidocaldarius geranylgeranyl diphosphate synthase: Analysis using mutated enzymes and artificail allylic substrates. J. Biol. Chem., 123, 6, 1036-1040 (1998)
N. Shimizu, T. Koyama, K. Ogura: Molecular cloning, expression and purification of undecaprenyl diphosphate synthase: No sequence similarity between E- and Z-prenyl diphosphate synthases. J. Biol. Chem., 273 (31), 19476-19481 (1998)
A. Koike-Takeshita, T. Koyama, K. Ogura: Intersubunit structure within the heterodimers of medium-chain prenyl diphosphate synthases: Formation of a hybrid-type heptaprenyl diphosphate synthase. J. Biochem., 124 (2), 790-797 (1998)
Y.-W. Zhang, T. Koyama, D. M. Marecak, G. D. Prestwich, Y. Maki, K. Ogura: Two subunits of heptaprenyl diphosphate synthase of Bacillus subtilis form a catalytically active complex. Biochemistry, 37 (38), 13411-13420 (1998)
M. Nagaki, H. Kannari, J. Ishibashi, Y. Maki, T. Nishino, K. Ogura, T. Koyama: Substrate specificity of thermostable farnesyl diphosphate synthase with alkyl group homologs of isopentenyl diphosphate. Bioorg. Med. Chem. Lett., 8 (18), 2549-2554 (1998)
K. Ogura, T. Koyama: Enzymatic aspects of isoprenoid chain elongation. Chem. Rev., 98, 1263-1276 (1998)
古山種俊: ポリプレニル二リン酸合成酵素の構造と機能 -はじめて明らかにされたZ型プレニル鎖延長酵素の構造-. 生物工学, 76 (10), 422-426 (1998)
1997
M. Kataoka, M. Ikemi, T. Morikawa, T. Miyoshi, K. Nishi, M. Wada, H. Yamada, S. Shimizu: Isolation and characterization of D-threonine aldolase, a pyridoxal-5'-phosphate-dependent enzyme from Arthrobacter sp. DK-38. Eur. J. Biochem., 248, 385-393 (1997)
M. Kataoka, L.P.S. Rohani, K. Yamamoto, M. Wada, H. Kawabata, K. Kita, H. Yanase, S. Shimizu: Enzymatic production of ethyl (R)-4-chloro-3-hydroxybutanoate: Asymmetric reduction of ethyl 4-chloro-3-oxobutanoate by an Escherichia coli transformant expressing the aldehyde reductase gene from yeast. Appl. Microbiol. Biotechnol., 48, 699-703 (1997)
M. Kataoka, M. Wada, K. Nishi, H. Yamada, S. Shimizu: Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39: FEMS Microbiol. Lett., 151, 245-248 (1997)
J-Q. Liu, T. Dairi, M. Kataoka, S. Shimizu, H. Yamada: L-allo-Threonine aldolase from Aeromonas jandaei DK-39: Gene cloning, nucleotide sequencing and identification of the pyridoxal 5'-phosphate-binding lysine residue by site-directed mutagenesis. J. Bacteriol., 179, 3555-3560 (1997)
J-Q. Liu, S. Nagata, T. Dairi, H. Misono, S. Shimizu, H. Yamada: The GLY1 gene of Saccharomyces cerevisiae encodes a low-specific L-threonine aldolase that catalyzes cleavage of L-allo-threonine and L-threonine to glycine: Expression of the gene in Escherichia coli and purification and characterization of the enzyme. Eur. J. Biochem., 245, 289-293 (1997)
T. Sugai, T. Yamazaki, M. Yokoyama, H. Ohta: Biocatalysis in Organic Synthesis: The use of nitrile- and amide-hydrolyzing microorganisms. Biosci. Biotech. Biochem., 61, 1419-1427 (1997)
T. Sugai, M. Yokoyama, T. Yamazaki, H. Ohta: Pivotal role of (E)-3-carbamoyl-1-propenylboronic acid in the combination of SuzukiﾐMiyaura coupling and enzyme reactions: Synthesis of (3E,5E)- and (3E,5Z)-6-phenyl-3,5-hexadienoic acid. Chem. Lett., 797-798 (1997)
太田博道: 水の中でのカルバニオンの化学. 化学と生物, 35, 799-807 (1997).
S. Kadowaki, I. Saskiawan, J. Watanabe, K. Yamamoto, M. Bunno, Y. Ichihara, H. Kumagai: Transglycosylation activity of β-N-Acetylhexosaminidase from Penicillium oxalicum and its application to synthesis of a drug carrier. J. Ferment. Bioeng., 83 (4), 341-345 (1997)
K. Matsuda, T. Inazu, K. Haneda, M. Mizuno, T. Yamanoi, K. Hattori, K. Yamamoto, H. Kumagai: The chemo-enzymatic synthesis and evaluation of oligosaccharide-branched cyclodextrins. Bio. Med. Chem. Lett., 7 (18), 2353-2356 (1997)
N. Nunoura, T. Fujita, K. Ohdan, M. Kirihata, K. Yamamoto, H. Kumagai: Structural analysis of disaccharides synthesized by β-D-glucosidase of Bifidobacterium breve clb and their assimilation by Bifidobacteria. Biosci. Biotech. Biochem., 61 (6), 1033-1035 (1997)
Y.-W. Zhang, T. Koyama, K. Ogura: Two cistrons of the gerC operon of Bacillus subtilis encode the two subunits of heptaprenyl diphosphate synthase. J. Bacteriol., 179 (4), 1417-1419 (1997)
A. Koike-Takeshita, T. Koyama, K. Ogura: Identification of a novel gene cluster participating in menaquinone (vitamin K2) biosynthesis: Cloning and sequence determination of the 2-heptaprenyl-1,4-naphthoquinone methyltransferase gene of Bacillus stearothermophilus. J. Biol. Chem., 272 (19), 12380-12383 (1997)
M. Nagaki, T. Koyama, T. Nishino, K. Shimizu, Y. Maki, K. Ogura: An artificial substrate for the thermostable farnesyl diphosphate synthase from Bacillus stearothermophilus. Chem. Lett., 497-498 (1997)
J. Tangpakdee, Y. Tanaka, K. Ogura, T. Koyama, R. Wititsuwannnakul, D. Wititsuwannakul, K. Asawatreratanakul: Isopentenyl diphosphate isomerase and prenyl transferase activities in bottom fraction and C-serum from Hevea Latex. Phytochemistry, 45 (2), 261-267 (1997)
J. Tangpakdee, Y. Tanaka, K. Ogura, T. Koyama, R. Wititsuwannnakul, D. Wititsuwannakul: Rubber formation by fresh bottom fraction of Hevea Latex. Phytochemistry, 45 (2), 269-274 (1997)
J. Tangpakdee, Y. Tanaka, K. Ogura, T. Koyama, R. Wititsuwannnakul, N. Chareonthiphakorn: Structure of in vitro synthesized rubber from fresh bottom fraction of Hevea Latex. Phytochemistry, 45 (2), 275-281 (1997)
N. Ohya, Y. Tanaka, K. Ogura, T. Koyama: Isopentenyl pyrophosphate isomerase activity in Lactarius mashrooms. Phytochemistry, 45 (6), 1115-1118 (1997)
D. M. Marecak, Y. Horiuchi, H. Arai, M. Shimonaga, Y. Maki, T. Koyama, K. Ogura, G. D. Prestwich: Benzoylphenoxy analogs of isoprenoid diphosphates as photoactivatable substrates for bacterial prenyltransferases. Bioorg. Med. Chem. Lett., 7 (15), 1973-1978 (1997)
